编辑: 达达恰西瓜 | 2019-07-12 |
Thesemedicinesarecontrolledsubstancesundertheinternationaldrugcontrolconventions.Thesemedicinesarenotavailableinmanycountriesduetoarangeofissues,includingthecostofmedicinesanddifficultieswithprocurement.Thisdatabaseaimstoraiseawarenessofcurrentpricesandsourcesofmethadone,buprenorphine,andmorphineinordertoincreasetheiravailability. , Opioidsubstitutiontherapywithmethadoneand/orbuprenorphineisaneffective,evidence-basedtreatmentforopioiddependence.IthelpstoreducethetransmissionofHIVamonginjectingdrugusers.In2005,WHOaddedmethadoneandbuprenorphinetotheWHOModelListofEssentialMedicines. , TheWHO/HIVDepartment,incollaborationwiththeWHODepartmentofMentalHealthandSubstanceAbuseandtheDepartmentofMedicinesPolicyandStandards,iscollectinginformationfromthepharmaceuticalcompaniesproducinganddistributingmethadone,buprenorphine,ormorphine.Thisdataincludes,theavailableformsandformulations,procurementissues,registrationproceduresandprices.Thisdatabasewillprovidecountriesandorganizationspurchasingtheseessentialmedicineswithinformationtoimproveaccesstothesemedications. , , Disclaimer , Disclaimer , , Producerofcontrolledmedicines(finishedformulation) , Buprenorphine , Methadone , Morphine , , Quotedpriceandtreatmentcost(perpatientperyeartreatment)* , Buprenorphine , Methadone , Morphine , , Producerandcostofactivepharmaceuticalingredients , Buprenorphine , Methadone , Morphine , , ReferenceMaterial , ReferenceMaterial , , InportandExport , Exportrequirements , *basedonWHOrecommendeddailydose ,,
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WHOhascompiledthedatainthetablebelow,however,theinformationrepresentedinthetableshasbeenprovidedandvalidatedexclusivelybythemanufacturers.Thisinformationwillbeupdatedasnewdatabecomesavailable,includingWHO'
ssix-monthlysurveys.WHOhasmadeeveryefforttoensuretheaccuracyoftheinformationpresentedinthisreport,butthereadersshouldbearinmindthatthisisahighlydynamicarea,andthatdatacanthereforeneverbecomplete.ThedataandinformationcontainedhereinarebeingprovidedasreceivedandWHOmakesnorepresentationsorwarranties,eitherexpressedorimplied,astotheiraccuracy,completenessorfitnessforaparticularpurpose.WHOacceptsnoresponsibilityorliabilitywithregardtotherelianceon,oruseof,suchdataandinformation.Thementionofspecificcompaniesorofcertainmanufacturers'
productsdoesnotimplythattheyareendorsedorrecommendedbyWHOinpreferencetoothersofasimilarnaturethatarenotspecificallymentioned. ,,
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sattentionisalsodrawntotheimportanceofqualityassuranceforpharmaceuticalproducts.Licensingauthoritiesinthecountriesoforiginareexpectedtoberesponsibleforthereviewandapprovalofthedetailedcompositionandformulationwhenauthorizingapharmaceuticalproducttobemarketed,includingthespecificationsofitsingredients,assubmittedbythemanufacturerofthedosageform,andtooverseecompliancewithGoodManufacturingPracticerequirementsasrecommendedbyWHO.Errorsoromissionsexcepted,thenamesofproprietaryproductsaredistinguishedbyinitialcapitalletters.Thedesignationsemployedandthepresentationofthematerialinthisreport,includingtables,donotimplytheexpressionofanyopinionwhatsoeveronthepartofWHOconcerningthelegalstatusofanycountry,territory,cityorareaorofitsauthorities,orconcerningthedelimitationofitsfrontiersorboundaries. ,,
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Companiesproducingbuprenorphine,methadoneandmorphineasactivepharmaceuticalingredientsand/orfinishedformulationthatarenotrepresentedinthisdatabaseareencouragedtocontactamds@who.intfortheinclusionoftheirinformationinthedatabase. ,,